Genetic diseases conferring resistance to infectious diseases

نویسندگان

  • Isabelle C. Withrock
  • Stephen J. Anderson
  • Matthew A. Jefferson
  • Garrett R. McCormack
  • Gregory S.A. Mlynarczyk
  • Aron Nakama
  • Jennifer K. Lange
  • Carrie A. Berg
  • Sreemoyee Acharya
  • Matthew L. Stock
  • Melissa S. Lind
  • K. C. Luna
  • Naveen C. Kondru
  • Sireesha Manne
  • Bhavika B. Patel
  • Kuei-Pin Huang
  • Shaunik Sharma
  • Hilary Z. Hu
  • Sri Harsha Kanuri
  • Steve A. Carlson
چکیده

Genetic diseases conferring resistance to infectious diseases Isabelle C. Withrock , Stephen J. Anderson , Matthew A. Jefferson , Garrett R. McCormack , Gregory S.A. Mlynarczyk , Aron Nakama , Jennifer K. Lange , Carrie A. Berg , Sreemoyee Acharya , Matthew L. Stock , Melissa S. Lind , K.C. Luna , Naveen C. Kondru , Sireesha Manne , Bhavika B. Patel , Bierlein M. de la Rosa , Kuei-Pin Huang , Shaunik Sharma , Hilary Z. Hu , Sri Harsha Kanuri , Steve A. Carlson *

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Genetic Diversity and Drug Resistance of Helicobacter pylori Strains in Isfahan, Iran

Objective(s) Resistance to antimicrobial agents, particularly metronidazole and clarithromycin, is frequently observed in Helicobacter pylori and may be associated with treatment failure. This resistance rate varies according to the population studied. The aim of this study was to assess the pattern of antimicrobial resistance of H. pylori isolates from dyspeptic patients in Isfahan. Material...

متن کامل

Amino acid Substitution Mutations Analysis of gyrA and parC Genes in Clonal Lineage of Klebsiella pneumoniae conferring High-Level Quinolone Resistance

Background: Emergence Klebsiella pneumoniae resistant to quinolone antibiotics due to mutations in gyrA and parC genes created problem for treatment of patients in different hospitals in Iran. The objective of this study was to determine the amino acid substitutions of GyrA and ParC proteins in certain clonal lineages of the K. pneumoniae conferring high level quinolone resistance. Methods: One...

متن کامل

Application of bacterial shuttle vectors in designing new vaccines against infectious diseases: brief report

Background: Today, several vaccines have been developed to prevent infectious diseases. The older first-generation vaccines may have many problems. In this regard, genetic engineering plays an important role using tools such as shuttle vectors to develop recombinant DNA vaccines that usually include plasmid constructed so that can propagate in two different host species. The present study revie...

متن کامل

Clinical implications of genotypic resistance to the newer antiretroviral drugs in HIV-1-infected patients with virological failure.

Virological suppression rates achieved with the new antiretroviral drugs in patients with virological failure and resistance to multiple drug classes are nearly matching the rates seen in treatment-naive patients. Knowledge of cross-resistance patterns to drugs of the same class is key for successful use of etravirine, tipranavir, and darunavir in treatment-experienced patients. Determination o...

متن کامل

Kin selection and evolution of infectious disease resistance.

Discoveries of mutations conferring resistance to infectious diseases have led to increased interest in the evolutionary dynamics of disease resistance. Several recent papers have estimated the historical strength of selection for mutations conferring disease resistance. These studies are based on simple population genetic models that do not take account of factors such as spatial and family st...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015